Meropenem Injection is used for complicated skin and soft tissue infection, complicated infections occurring within the stomach cavity, inflammation of the brain and spinal cord membranes (bacterial meningitis), or infection during or following childbirth (intra or post-partum infections). (meropenem for injection) and other antibacterial drugs, MERREM I.V. Each vial is for single use only. It works by killing bacteria that cause infection. For intravenous infusion meropenem vial may be directly constituted with 0.9% sodium chloride or 5% glucose (dextrose) solutions for infusion. How To Use. Indications for MERREM IV (meropenem injection) refers to the medical reasons for why MERREM IV is used and recommended as a treatment. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. The dose depends on what type of infection you have, where it is in the body and how serious it is. This medication is known as a carbapenem-type antibiotic. Many patients receiving meropenem for injection are severely ill, have multiple background diseases, physiological impairments and receive multiple other drug therapies. Test solution— Transfer an accurately measured volume of Injection, equivalent to about 50 mg of meropenem, based on the labeled amount, to a 10-mL volumetric flask, dilute with Solvent to volume, and mix. If you have any questions, ask your doctor or pharmacist. Halopéridol injectable, USP Médicaments IV et infos sur la sécurité Télécharger la monographie du produit Notification relativement aux fiches de données de sécurité. Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient. 5 mg/mL, fiole DM, 1 mL. Meropenem Kabi is not recommended for use in children under the age of 3 months. Meropenem is used to treat a wide variety of bacterial infections. Counsel patients that antibacterial drugs including meropenem for injection should only be used to treat bacterial infections. MEROPENEM 125MG INJECTION. Meropenem to be used for bolus intravenous injection should be constituted with sterile water for injection. Discard any residue. Pronunciation (MER-oh-PEN-em) Brand name(s) Merrem . Meropenem for Injection. This medicine is given by drip or by direct injection into a vein, under the supervision of a healthcare professional. It works by killing the bacteria or preventing their growth. INDICATIONS AND USAGE. Meropenem for Injection; Print. Meropenem के लाभ और उपयोग करने का तरीका- Meropenem Benefits & Uses in Hindi Meropenem की खुराक और इस्तेमाल करने का तरीका- Meropenem Dosage & How to Take in Hindi DESCRIPTION MERREM® I.V. Learn how to use Aspen Meropenem, and it's dosage, warnings, side-effects, and more. In LRTI, bacteriological response rates at the end of therapy were 91% for both meropenem 500 mg tds and ceftazidime 1 g tds, and 91% for meropenem 500 mg bd compared with 86% for imipenem/cilastatin 500 mg bd. Rapid Life Drugs & Healthcare. Accidental overdosage could occur during therapy, particularly in patients with renal impairment. You will need to discuss the benefits and risks of using meropenem 500 MG Injection while you are pregnant. (meropenem for injection) … Use of meropenem for injection may lead to the development of a positive direct or indirect Coombs test. Injection. Meropenem may also be used for purposes not listed in this medication guide. Tobramycine pour injection; Vasopressine injectable; Accueil; Produits et Services; Médicaments IV; Halopéridol injectable, USP; Print. In … It exerts its bactericidal action by interfering with bacterial cell wall synthesis. Know Meropenem 500 MG Injection uses, side-effects, composition, substitutes, drug interactions, precautions, dosage, warnings only on Lybrate.com Learn how to use Meropenem, and it's dosage, warnings, side-effects, and more. Meropenem for Injection should be used during pregnancy only if the potential benefit justifies the potential risk to mother and fetus. They do not treat viral infections (e.g., the common cold). 5 mg/mL, fiole DM, 1 mL. Solutions of meropenem injection should not be frozen. (8.4) • Renal Impairment: Dose adjustment is necessary, if creatinine /min or less. The mean meropenem concentrations reconstituted in normal saline solution decreased 1.66%, 3.31% and 5.80% after 2, 4 and 8 hours storage at 20 degrees C, respectively. The pharmacological properties and mode of administration make it unlikely that intentional overdose will occur. Treonam 1000 mg Injection is commonly used to treat critically ill patients admitted to the hospital. If you stop using meropenem and vaborbactam injection too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics. Meropenem injection is used to treat skin and abdominal (stomach area) infections caused by bacteria and meningitis (infection of the membranes that surround the brain and spinal cord) in adults and children 3 months of age and older. DESCRIPTION. Chromatographic apparatus and conditions . meropenem 500 MG Injection should be used with extreme caution in CHILDREN younger than 3 months old; safety and effectiveness in these children have not been confirmed. Your doctor may have prescribed it for another reason. Strikeout items have been removed, underline items have been added. How to use. Use meropenem and vaborbactam injection until you finish the prescription, even if you feel better. Contraindications and precautions Hypersensitivity to Penicillins, Cephalosporins and Carbapenems. Read the Patient Information Leaflet if available from your pharmacist before you start using meropenem and each time you get a refill. Caution in infants with impaired renal or hepatic function. Colitis - due to risk of pseudomembranous colitis. (meropenem for injection) FOR INTRAVENOUS USE ONLY To reduce the development of drug-resistant bacteria and maintain the effectiveness of MERREM® I.V. FDA REQUESTED LABELING CHANGES AS PER THE AGENCY REVIEW . Overdosage. Aspen Meropenem Injection is used for complicated skin and soft tissue infection, complicated infections occurring within the stomach cavity, inflammation of the brain and spinal cord membranes (bacterial meningitis), or infection during or following childbirth (intra or post-partum infections). Meropenem powder for injection (Demo SA, Noriderm Enterprises, Nicosia, Cyprus) was supplied by the Royal Derby Hospital pharmacy stores. It is (4R,5S,6S)-3-[[(3S,5S)-5-(Dimethylcarbamoyl)-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid trihydrate. 500 mg SD Vial 20 mL; 1 g SD Vial 20 mL; 500 mg SD Vial 20 mL IV Drugs Product & Safety Information Download Product Monograph Safety Data Sheet Notification. Meropenem, sold under the brandname Merrem among others, is a broad-spectrum antibiotic used to treat a variety of bacterial infections. View Meropenem’s uses, side-effects, drug interactions, expert advice and user FAQs only on 1mg.com. Infusion. Use of Meropenem must be discussed with the Infectious Diseases Team. Injection. It works by stopping the growth of bacteria. This medicine is to be given only by or under the direct supervision of your doctor. Meropenem is also used to treat bacterial meningitis (infection of brain or spinal cord). This medication is given by injection into a vein as directed by your doctor, usually every 8 hours. Treatment of overdosage should be symptomatic. Meropenem injection is used to treat infections caused by bacteria. Meropenem Injection 500MG Meropenem is used to treat severe infections of the skin or stomach. Merrem® IV (meropenem for Injection) NDA 50706 . should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. Each vial is for single use only. Ask your doctor if you have any questions about why this medicine has been prescribed for you. Meropenem is not addictive. Twelve lots of (0.5 g meropenem in normal saline) solution were evaluated in each temperature condition. Meropenem - injection. Reproduction studies have been performed in rats and Cynomolgous monkeys at doses up to 1000 mg/kg/day (approximately 16 times the usual human dose of 1 g every 8 hours). It penetrates bacterial cell walls, its high level of stability to all serine beta-lactamases and its marked affinity for the Penicillin Binding Proteins (PBPs.). Infusion. Use on one patient on one occasion only. Citrate (0.3% w/v) buffered sodium chloride pH 7, 100 mL, was supplied by Preston Pharmaceuticals (Royal Preston Hospital, Preston, UK). Meropenem to be used for bolus intravenous injection should be constituted with sterile water for injection. • Pediatric use: Meropenem for Injection and Sodium Chloride Injection should not be used in pediatric patients who require less than the full adult dose of meropenem. VABOMERE ® (meropenem and vaborbactam) for injection, for intravenous use Initial U.S. Approval: 2017. Meropenem is used in the treatment of Severe bacterial infections. Meropenem is an injection and is usually only used in hospitals. It is available only with a doctor's prescription. At follow-up, the response rates were 87%, 77%, 84% and 79%, respectively. Caution in infants with history of seizures. Below is a summary of known side effects for MERREM IV. For intravenous infusion meropenem vial may be directly constituted with 0.9% sodium chloride or 5% glucose (dextrose) solutions for infusion. ADVERSE REACTIONS Adverse Drug Reaction Overview Meropenem for injection is generally well tolerated. Meropenem injection is in a class of medications called antibiotics. Meropenem is a carbapenem antibiotic for parenteral use . (meropenem) for Injection, for Intravenous Use. Compatibility of Y-site Injection of Meropenem Trihydrate With 101 Other Injectable Drugs. Meropenem 500 MG Injection is used for Bacterial Meningitis, Skin And Structure Infection, Intra-Abdominal Infections etc. Some of these include meningitis, intra-abdominal infection, pneumonia, sepsis, and anthrax. MERREM ® IV (meropenem for injection) is a sterile, pyrogen-free, synthetic, carbapenem antibacterial for intravenous administration. (2.2, 8.6) 5/2020 Reference ID: 4607155 Uses. VABOMERE (meropenem and vaborbactam) is a combination of meropenem, a penem antibacterial, and vaborbactam, a beta-lactamase inhibitor, indicated for the treatment of patients 18 years and older with complicated urinary tract infections (cUTI) including … This medicine will not work for colds, flu, or other virus infections. It is given by injection into a vein.. Common side effects include nausea, diarrhea, constipation, headache, rash, and pain at the site of injection. Hosp Pharm 2019 4326 Revue Curti C, Harti Souab K, Lamy E, Mathias F, Bornet C, Guinard B, Fersing C, Primas N, Alban?se J, Vanelle P. Stability studies of antipyocyanic beta-lactam antibiotics used in continuous infusion Pharmazie 2019 ; 74, 6: 357-362. Use this Test solution immediately. Side Effects for MERREM IV (meropenem injection) are also known as adverse reactions. All treatments were well tolerated.